Issue 2June 2015
Special report

Impact of the microbiota on the gut-brain axis: from physiology to disease

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    The brain, under the influence… This is the direction neuroscience has been taking for just over 10 years. We long thought that the central nervous system was closed, partitioned behind barriers, notably the blood-brain barrier, not readily permeable to external influences. It soon became evident that neurology could not escape the very principles of integrated systems.

    Brain development and plasticity are eminently dependent on numerous extrinsic stimuli (environment, exercise, social relations, etc.) and intrinsic stimuli (interdependent systems and metabolism, etc.). Yet, far back, the microbiota, particularly the gut microbiota, could be suspected as having a direct influence on neurological disease. Evidence abounds and this influence appears to be exerted via two main pathways: either the enteric nervous system, or via significant changes to the immune system. It is therefore natural to dedicate the second special issue of La Revue des Microbiotes to neurology.

    The editorial board would like to thank the authors of this issue for their outstanding work in allowing us to glimpse new prospects in our patient management, particularly in neurodegenerative diseases such as Parkinson’s disease or multiple sclerosis.

    Table of contents

    • Special Report

      • Impact of the microbiota on the gut-brain axis: from physiology to pathology
        Scientific committee : Patrick Vermersch
        Contributors :
    • The Microbiota Chronicle

      • AAN 2015 Annual Meeting. American Academy of Neurology® 18-25 February 2015. Washington, DC (USA)
        Scientific committee : Patrick Vermersch
      • AAAAI Annual Meeting - American Academy of Allergy, Asthma & Immunology. 20-24 February 2015. Houston (USA)
        Scientific committee : Cyrille Hoarau
      • Probiota 2015 – 3-5 février 2015. Amsterdam
        Scientific committee : Jean-Marc Bohbot
      • 2nd international workshop on lung health. COPD: new challenges, new solutions. 19-21 février 2015. Valencia
        Scientific committee : Jacques Amar
      • The Liver Meeting® 2014 - AASLD (American Association for the Study of Liver Diseases). 07-11 novembre 2014. Boston (USA)
        Scientific committee : Stanislas Bruley des Varannes
    • Microbiota News

      • Health claims in Europe: a complicated situation?
        Scientific committee : Bruno Pot
    • In Brief

    • Interview

      • Autistic disorders : gut bacteria to blame?
        Contributors : Marion Leboyer, Alexandru Gaman
    • Focus


    • Interview

      Alexandru Gaman

    • Interview

      Marion Leboyer

    Scientific committee

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