Issue 26 june 2023 Special Report Microbiota and rheumatology: A new research focus
Microbiome and joint inflammation: The missing link?
The detection of dysbioses over the course of joint inflammation pathologies naturally leads us to question their relation to the latter: Cause or consequence?
The interventional studies necessary to answer this question remain limited to animal models, in which possible causality is suggested with the loss of protective commensal bacterial species and excessive proinflammatory species.
To test its causality and offer new treatment solutions for patients, this imbalance needs to be corrected.There are several potential approaches: The simplest, although it is sure to be insufficient in many cases, is to improve the patient's lifestyle, particular in terms of diet; on the other end of the spectrum, the most radical approach involves the transplantation of a eubiotic microbiota, trials of which have delivered promising results in inflammatory gut conditions and which may lead to experimental treatments being extended to joint conditions.
Editor in Chief of this issue
Table of contents
- Microbiota and rheumatology: A new research focusIn collaboration with Maxime Breban and Claire Daien
- Ulrich Meinzer
The Microbiota Chronicle
- Illustrated feature: The different types of RNA and their functionsBruno Pot
- Faecal transplantation for failures in immunological check-point inhibitors in oncology: How to find the right donorCyrille Hoarau
- Microbiome - Where does our microbiota come from? The broadest study conducted to date on the topic answers the questionAlexis Mosca
- Gastroenterology - Physical activity: Get hydrogen production going!Stanislas Bruley des Varannes
- Metabolism - Tell me about your microbiota, and I'll tell you how long you're able to run for!Philippe Gérard
- Cardiology - The gut microbiota, a therapeutic target for high blood pressureJacques Amar
- Paediatrics - « Let them have their fun in the sand! It's good for their microbiota, and good for their health! »Cyrille Hoarau
- Gynaecology - When postbiotics become prebiotics…Jean-Marc Bohbot
- Biotics - new conservative approach to microbiota decolonisationGeneviève Héry-Arnaud
Dossier thématiqueProf. Maxime Breban
Rheumatologist, Ambroise-Paré Hospital, Boulogne-Billancourt
Dossier thématiqueProf. Claire Daien
University Professor - Hospital Practitioner, Department of Rheumatology, Lapeyronie University Teaching Hospital, Montpellier & University of Montpellier Inserm U1046, CNRS UMR 9214, University of Montpellier Physiology and Experimental Medicine of the Heart and Muscles (PhyMedExp), Montpellier, France
EntretienProf. Ulrich Meinzer
Department of General Paediatrics at the Robert-Debré Hospital, Paris