Issue 2 june 2015 Thematic Report Impact of the microbiota on the gut-brain axis: from physiology to disease
The brain, under the influence… This is the direction neuroscience has been taking for just over 10 years. We long thought that the central nervous system was closed, partitioned behind barriers, notably the blood-brain barrier, not readily permeable to external influences. It soon became evident that neurology could not escape the very principles of integrated systems.
Brain development and plasticity are eminently dependent on numerous extrinsic stimuli (environment, exercise, social relations, etc.) and intrinsic stimuli (interdependent systems and metabolism, etc.). Yet, far back, the microbiota, particularly the gut microbiota, could be suspected as having a direct influence on neurological disease. Evidence abounds and this influence appears to be exerted via two main pathways: either the enteric nervous system, or via significant changes to the immune system. It is therefore natural to dedicate the second special issue of La Revue des Microbiotes to neurology.
The editorial board would like to thank the authors of this issue for their outstanding work in allowing us to glimpse new prospects in our patient management, particularly in neurodegenerative diseases such as Parkinson’s disease or multiple sclerosis.
Table of contents
- Impact of the microbiota on the gut-brain axis: from physiology to pathologyPatrick Vermersch, Valérie Daugé
- AAN 2015 Annual Meeting. American Academy of Neurology® 18-25 February 2015. Washington, DC (USA)Patrick Vermersch
- AAAAI Annual Meeting - American Academy of Allergy, Asthma & Immunology. 20-24 February 2015. Houston (USA)Cyrille Hoarau
- Probiota 2015 – 3-5 février 2015. AmsterdamJean-Marc Bohbot
- 2nd international workshop on lung health. COPD: new challenges, new solutions. 19-21 février 2015. ValenciaJacques Amar
- The Liver Meeting® 2014 - AASLD (American Association for the Study of Liver Diseases). 07-11 novembre 2014. Boston (USA)Stanislas Bruley des Varannes
- Autistic disorders : gut bacteria to blame?Marion Leboyer, Alexandru Gaman